Crystallisation Science and Engineering

About the course

What will I learn?
This three-day short course, delivered by academic and industrial experts, will outline the fundamental science and engineering of crystallisation processes.

How will I benefit?
On completion of the course, you’ll have a deeper understanding of crystallisation science and technology to assist in process development and scale-up for the manufacture of crystals with desired properties.

Who should attend?

This course is for you if you’re an engineer or scientist working in industries such as agrochemicals, biotechnology, food, fuels, personal care, pharmaceutical and speciality chemicals companies. It is relevant to those involved in crystallisation process development, scale-up, control and operations. It will also be of interest if you’re a postgraduate or post-doc involved in research in the general area of crystallisation.


Provisional programme

The course will include case studies and laboratory experimental sessions to demonstrate crystallisation processes, application of advanced process analytical technologies (PATs) and particle characterisation techniques. You’ll also have hands-on opportunities to use crystallisation modelling software.

Please note that due to limited capacities in our labs currently, we may not be able to run the live lab demonstrations.

Day one: Crystallisation Fundamentals

  • Crystallisation route map

  • Nucleation and crystal growth

  • Crystal morphology and habit modification

  • Fundamentals of polymorphism

  • Solid-State Analysis

  • Screening for polymorphs (solid form selection)

  • Characterisation of pseudo polymorphs (TGA, DVS, IGC)

  • Laboratory Demonstrations - D1 - Nucleation Kinetics and D2 – Growth Kinetics

Day two: Crystallisation Processes

  • Batch crystallisation processes

  • Hydrodynamics, mixing and heat transfer in batch crystallisers

  • Continuous crystallisation processes

  • Solvent selection: properties and solubility

  • Workflow for crystallisation process development – a case study

  • Post crystallisation unit operations: Filtration and drying

Measurements and Control

  • Particle size and shape measurements and characterisation

  • Control of crystallisation processes for PSD

  • Process spectroscopic techniques (IR, UV-vis, Raman)

  • Laboratory Demonstrations - D3 - Particle characterisation and D4 - Raman spectroscopy

Day three: Measurements & Control cont...

  • Process spectroscopic techniques (IR, UV-vis, Raman)

  • Particle properties and performance

  • Fundamentals of co-crystallisation and case studies of recent developments

  • Molecular to crystal science modelling route map

  • Software demonstration: VISUAL HABIT

  • Digital design of crystallisation process

  • Software demonstration: Introduction to the crystallisation modules of gPROMS FormulatedProducts (Simulation and Global System Analysis)


Course directors:

Dr Tariq Mahmud - University of Leeds

Dr Xiaojun Lai - University of Leeds

Fee information



Fees are VAT exempt.

Course fees includes:

  • cost of tuition

  • course materials

  • lunches

  • refreshments

View our terms and conditions

Venue details

Faculty of Engineering and Physical Sciences
University of Leeds

Detailed directions (including the exact location for the course registration and presentation room) will be sent out with the delegate joining instructions.

How to find us

The nearest public car park is Woodhouse Lane (multi storey) at LS1 3HQ. The car park is open 24 hours. Charges apply, please click here for information and location details. Please note this car park is a fifteen minute walk to/ from our building and delegates should allow ample time to park and register for the course. 

Car parking for visitors is unavailable at the University.

There is also limited on-street parking in the vicinity of the University.


You are responsible for your own accommodation, if required. A list of hotels close to the University will be sent with your course joining instructions.

What our delegates say

"Course was good, covered a variety of topics and catered for those in industry and academia" Almac Group Ltd

"It gave me a good understanding of crystal formation and analysis, which was everything I wanted from the course" Infineum UK Ltd

"The course offers a wide variety of topics which should appeal to people involved in all aspects of crystallisation or crystal work" University of Liverpool

Contact us

Katie Warner – Course Coordinator

CPD Conference and Events Unit
Faculty of Engineering and Physical Sciences 
University of Leeds,

T: +44 (0)113 343 8104