- Start date: 25 March 2024
- End date: 27 March 2024
- Duration: Three days
- Fees: £1,110 VAT exempt
- Venue: Faculty of Engineering and Physical Sciences, University of Leeds
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About the course
What will I learn?
This three day short course will outline the fundamental science and engineering of crystallisation processes. The programme embraces digital transformation and weaves together the best experimental and computational workflows. The course will include laboratory experimental sessions to demonstrate crystallisation processes, application of advanced process analytical technologies (PATs) and particle characterisation techniques. The delegates will also have first-hand opportunities to use crystallisation modelling software. The course will be delivered by leading academic and industrial experts in the field and will include case studies.
Delegates will leave with core knowledge that they can use in their industrial work and a deeper understanding of crystallisation science and technology to assist in process development and scale-up of the manufacture of crystals for desired properties. The course will also give delegates the tools and a knowledge framework to be able to better support company project teams and engage experts where needed.
Who should attend?
This course is for you if you’re an engineer or scientist working in industries such as agrochemicals, biotechnology, food, fuels, personal care, pharmaceutical and speciality chemicals companies. It is relevant to those involved in crystallisation process development, scale-up, control and operations. It will also be of interest if you’re a postgraduate or post-doc involved in research in the general areas of solid form selection, particle design and crystallisation.
Provisional programme – please note this is subject to change
Day one: Monday 25 March 2024
Registration 8.45 – 9.10am
Crystallisation route map
Solution properties and supersaturation generation
Nucleation and crystal growth
Fundamentals of polymorphism
D1 – Nucleation kinetics – Crystal16
D2 - Growth kinetics
Screening for polymorphs (solid form selection)
Solid-State Analysis for the characterisation of polymorphs and hydrates
Fundamentals of crystallisation and case studies of recent developments
Day two: Tuesday 26 March 2024
Crystallisation Process Engineering
Hydrodynamics, mixing and heat transfer in batch crystallisers
Workflow for crystallisation process development – a case study
Continuous crystallisation processes
Crystal morphology and habit modification
D3 – Particle characterisation
D3 part (1) Particle size measurement
D3 part (2) Insitu particle imaging
D4 – Raman spectroscopy
Laboratory Demonstrations continued
Post crystallisation unit operations: Filtration and drying
Measurements and Control
Process spectroscopic techniques (IR, UV-vis, Raman)
Control of crystallisation processes for PSD
Day three: Wednesday 27 March 2024
Particle size and shape measurements and characterisation (including properties and performance)
Crystallisation modelling and software demonstrations
Integrating computational and experimental crystallisation workflows to enable digital product design
CFD modelling of crystallisation processes
Digital design of crystallisation processes
Panel discussion and troubleshooting: experimental practices and best digital tools
Software demonstration: Visual Habit – enabling solid form and particle design
Software demonstration: Introduction to the crystallisation modules of gPROMS FormulatedProducts (Simulation and Global System Analysis)
Wrap-up and feedback from delegates
Day three ends at approximately 4.30pm
Dr Tariq Mahmud - School of Chemical and Process Engineering, University of Leeds
Dr Xiaojun Lai - School of Chemical and Process Engineering, University of Leeds
John Andrews, Clairet Scientific
Dr Alan Collier, Syngenta
Dr Bob Docherty, Visiting Professor, University of Leeds. Recently retired from Pfizer after 22 years having previously worked for ICI/Zeneca
Dr Siti Fatimah Ibrahim, University of Leeds
Dr John Hone, Syngenta
Professor Mingzhong Li, De Montford University, Leicester
Andy Maloney, Cambridge Crystallographic Data Centre
Christian Melches, GEA, Duisburg, Germany
Dr Niall Mitchell, Siemens Process Systems Enterprise (SPSE), London
Professor Anant Paradkar, University of Bradford
Professor Kevin Roberts, School of Chemical and Process Engineering, University of Leeds
Sarah Thompson, Technobis, Netherlands
Dr Umair Zafar, Novo Nordisk, Denmark
Fees are VAT exempt. Discounted fees apply to postgraduate students please contact Helen Forsyth.
Course fees includes:
cost of tuition
course dinner on Monday evening
View our terms and conditions
Faculty of Engineering and Physical Sciences
University of Leeds
Detailed directions (including the exact location for the course registration and presentation room) will be sent out with the delegate joining instructions.
The nearest public car park is Woodhouse Lane (multi storey) at LS1 3HQ. The car park is open 24 hours. Charges apply, please click here for information and location details. Please note this car park is a fifteen minute walk to/ from our building and delegates should allow ample time to park and register for the course.
Car parking for visitors is unavailable at the University.
There is also limited on-street parking in the vicinity of the University.
Delegates are responsible for organising your own evening meals and accommodation (if required). A list of hotels close to the University is available and will be provided with your course joining instructions.
What our delegates say
"Course was good, covered a variety of topics and catered for those in industry and academia" Almac Group Ltd
"It gave me a good understanding of crystal formation and analysis, which was everything I wanted from the course" Infineum UK Ltd
"The course offers a wide variety of topics which should appeal to people involved in all aspects of crystallisation or crystal work" University of Liverpool
Helen Forsyth – Course Coordinator
CPD Conference and Events Unit
Faculty of Engineering and Physical Sciences
University of Leeds,
T: +44 (0)113 343 8104
Course kindly sponsored by: