Crystallisation Science and Engineering

About the course

What will I learn?
This 3 day short course will outline the fundamental science and engineering of crystallisation processes. The programme embraces digital transformation and weaves together the best experimental and computational workflows. The course will include laboratory experimental sessions to demonstrate crystallisation processes, application of advanced process analytical technologies (PATs) and particle characterisation techniques. The delegates will also have first-hand opportunities to use crystallisation modelling software. The course will be delivered by leading academic and industrial experts in the field and will include case studies.

Course aims
Delegates will leave with core knowledge that they can use in their industrial work and a deeper understanding of crystallisation science and technology to assist in process development and scale-up of the manufacture of crystals for desired properties. The course will also give delegates the tools and a knowledge framework to be able to better support company project teams and engage experts where needed.

Who should attend?

This course is for you if you’re an engineer or scientist working in industries such as agrochemicals, biotechnology, food, fuels, personal care, pharmaceutical and speciality chemicals companies. It is relevant to those involved in crystallisation process development, scale-up, control and operations. It will also be of interest if you’re a postgraduate or post-doc involved in research in the general areas of solid form selection, particle design and crystallisation.


Provisional programme – please note this is subject to change

Day one: Monday 25 March 2024

Registration 8.45 – 9.10am

Crystallisation Fundamentals

  • Crystallisation route map

  • Solution properties and supersaturation generation

  • Nucleation and crystal growth

  • Fundamentals of polymorphism

  • Screening for polymorphs (solid form selection)

  • Solid-State Analysis for the characterisation of polymorphs and hydrates

  • Fundamentals of crystallisation and case studies of recent developments 

  • Practical lab demonstration – Nucleation Kinetics – Crystal 16

  • Practical lab demonstration – Growth Kinetics

Day two: Tuesday 26 March 2024

Crystallisation Process Engineering

  • Hydrodynamics, mixing and heat transfer in batch crystallisers

  • Workflow for crystallisation process development – a case study

  • Continuous crystallisation processes

  • Crystal morphology and habit modification

  • Post crystallisation unit operations: Filtration and drying

Measurements and Control

  • Process spectroscopic techniques (IR, UV-vis, Raman)

  • Control of crystallisation processes for PSD

  • Practical lab demonstration – Particle Characterisation

  • Practical lab demonstration – Raman Spectroscopy

Day three: Wednesday 27 March 2024

  • Particle size and shape measurements and characterisation

  • Particle properties and performance

Crystallisation modelling and software demonstrations

  • Digital design: integrating computational and experimental crystallisation workflows to enable product design

  • CFD

  • Digital design of crystallisation processes

  • Panel discussion and troubleshooting: experimental practices and best digital tools

  • Software demonstration: Visual Habit – enabling solid form and particle design

  • Software demonstration: Introduction to the crystallisation modules of gPROMS FormulatedProducts (Simulation and Global System Analysis

Day three ends at approximately 4.30pm


Course directors:

Dr Tariq Mahmud - School of Chemical and Process Engineering, University of Leeds

Dr Xiaojun Lai - School of Chemical and Process Engineering, University of Leeds

2023 Guest speakers:

John Andrews, Clairet Scientific
Dr Bob Docherty, Visiting Professor, University of Leeds. Recently retired from Pfizer after 22 years having previously worked for ICI/Zeneca
Dr Siti Fatimah Ibrahim, University of Leeds
Dr John Hone, Syngenta
Professor Mingzhong Li, De Montford University, Leicester
Andy Maloney, Cambridge Crystallographic Data Centre
Christian Melches, GEA, Duisburg, Germany
Dr Niall Mitchell, Siemens Process Systems Enterprise (SPSE), London
Dr Amgad Moussa, Syngenta, Switzerland
Dr Hien Nguyen, School of Computing, University of Leeds
Professor Anant Paradkar, University of Bradford
Professor Kevin Roberts, School of Chemical and Process Engineering, University of Leeds
Professor Sven Schroeder, University of Leeds
Dr Richard Storey, AstraZeneca, Macclesfield
Sarah Thompson, Technobis, Netherlands
Dr Tom Turner, School of Chemistry, University of Leeds
Dr Umair Zafar, Novo Nordisk, Denmark

Fee information



Fees are VAT exempt.

Course fees includes:

  • cost of tuition

  • course materials

  • lunches

  • refreshments

  • course dinner

View our terms and conditions

Venue details

Faculty of Engineering and Physical Sciences
University of Leeds

Detailed directions (including the exact location for the course registration and presentation room) will be sent out with the delegate joining instructions.

How to find us

The nearest public car park is Woodhouse Lane (multi storey) at LS1 3HQ. The car park is open 24 hours. Charges apply, please click here for information and location details. Please note this car park is a fifteen minute walk to/ from our building and delegates should allow ample time to park and register for the course. 

Car parking for visitors is unavailable at the University.

There is also limited on-street parking in the vicinity of the University.


Delegates are responsible for organising your own evening meals and accommodation (if required). A list of hotels close to the University is available and will be provided with your course joining instructions.

What our delegates say

"Course was good, covered a variety of topics and catered for those in industry and academia" Almac Group Ltd

"It gave me a good understanding of crystal formation and analysis, which was everything I wanted from the course" Infineum UK Ltd

"The course offers a wide variety of topics which should appeal to people involved in all aspects of crystallisation or crystal work" University of Liverpool

Contact us

Helen Forsyth – Course Coordinator

CPD Conference and Events Unit
Faculty of Engineering and Physical Sciences 
University of Leeds,

T: +44 (0)113 343 8104


Stay up to date with the latest course news and developments by following the CPD, Conference and Events unit on LinkedIn and Twitter.


Course kindly sponsored by:

CrystEngComm logo
Technobis logo
British Association for Crystal Growth