Dr Hannah Britt
- Position: Lecturer
- Areas of expertise: mass spectrometry; extracellular vesicles; dynamic disease mechanisms; chemical biology.
- Email: H.M.Chisholm-Britt@leeds.ac.uk
- Location: G34b School of Chemistry
- Website: Googlescholar | ORCID
Profile
I am a lecturer in the School of Chemistry, with scientific interests which fall at the interface between the fields of chemistry and biology. During my first foray into research at the University of Durham I applied this interest to focus on the use of biophysical methods, especially mass spectrometry, to study the reactivity of pharmaceuticals and antimicrobial peptides at the cell membrane, under the supervision of Drs John Sanderson and Jackie Mosely. After completing my PhD in 2018, I moved on to postdoctoral research with Professor Kostas Thalassinos (UCL) and Professor Dame Carol Robinson (Oxford). In these roles I focused on applying my mass spectrometry expertise into exploration of protein behaviour at the cell membrane, with a particular focus on probing features of disease-related and glycosylated proteins within their native environment. Since joining the University of Leeds as lecturer in 2024, I have focused on the development of novel mass spectrometry approaches to capture dynamic disease mechanisms directly from human tissue and biofluids, in an effort to revolutionise disease diagnosis and treatment.
Research interests
My group is focused on the development and application of structural mass spectrometry approaches to study dynamic disease mechanisms directly from human biofluids and tissues. We are also interested in how these molecular pathways are modulated by external factors, especially pharmaceuticals.
<h4>Research projects</h4> <p>Some research projects I'm currently working on, or have worked on, will be listed below. Our list of all <a href="https://eps.leeds.ac.uk/dir/research-projects">research projects</a> allows you to view and search the full list of projects in the faculty.</p>Qualifications
- PhD, University of Durham (2018)
- MSci, University of Durham (2014)
Professional memberships
- Biochemical Society
- British Mass Spectrometry Society
Student education
I teach mass spectrometry and biological chemistry at undergraduate level. I act as an academic tutor, and offer research projects for MChem and MNatSci final year students.
Research groups and institutes
- Chemical Biology and Medicinal Chemistry
- Organic
Projects
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<li><a href="//phd.leeds.ac.uk/project/2052-understanding-autoimmune-diseases-using-mass-spectrometry.">Understanding Autoimmune Diseases Using Mass Spectrometry.</a></li>