High-performance liquid chromatography (HPLC)

We have a number of HPLC instruments for analytical and preparative work. A range of chiral columns are also available for ee determination. 

Equipment

  • 2 x Agilent 1290 series HPLC systems. These systems perform the majority of our analytical work. The high pressure ratings enable them to be used with rapid resolution columns enabling run time to be shortened to minutes for many applications. UV , fluorescence and evaporative light scattering detection available.
  • Agilent 1260 Mass Directed Preparative HPLC. Walk up mass directed prep- HPLC system connected to a mass spectrometer – simply specify the mass of your target compound and the system will only collect peaks of the appropriate compound.
  • Agilent 1260 Preparative HPLC. For uv directed fraction collection.

Applications

Analysis and quantitation of purity, purification of small molecules and peptides.

Who can use the facility?

We are committed to sharing our facilities and associated expertise with external academic and industrial collaborators. To make an enquiry please email Dr Stuart Warriner, e: s.l.warriner@leeds.ac.uk

Location

School of Chemistry, G61