Dr Paul Thornton
- Module Leader
- Programme Manager
My research is concerned with employing controlled polymerisation techniques to produce functional polymeric materials with applicability within both a biomedical context and in the enhancement of commercially-important processes. Contemporary polymerisation methodologies including reversible addition−fragmentation chain-transfer polymerisation (RAFT), atom transfer radical polymerisation (ATRP) and nitroxide-mediated radical polymerization (NMP) are utilised to produce distinct (co)polymers for designed use in separation science, catalysis, (bio)sensing and surface coating applications.
In addition, I also have an interest in controlled ring-opening polymerisation to yield biodegradable polymers (homopolypeptides and polyesters) that are highly promising candidates as biomaterials. N-carboxyanhydride polymerisation is a facile route to creating synthetic homopolypeptides that possess a range of functionalities dependent on the amino acid monomer selected, and the capability to adopt a secondary structure. Consequently, we have exploited these features to create homopolypeptides that are capable of forming hydrogels, add antimicrobial properties and hydrophilicity to siloxane surfaces, and form enzyme-degradable carriers for gene delivery.
Finally, I am interested in utilising suspension and emulsion polymerisation, in addition to microfluidic synthesis, to create functionalised nanoparticles and resins. Further modification of the nanoparticles produced via solid phase peptide synthesis enables the creation of a range of stimuli-responsive materials that may be utilised in chromatography, catalyst immobilisation or drug delivery applications.
In addition to my teaching responsibilities, I also provide MCHEM and MSc project supervision.
Research groups and institutes
- Crystallisation and Directed Assembly
- Colour and Polymer Science
Current postgraduate researchers
<li><a href="//phd.leeds.ac.uk/project/206-novel-polymer-architectures-for-controlled-release-applications">Novel Polymer Architectures for Controlled Release Applications</a></li>
<li><a href="//phd.leeds.ac.uk/project/1033-stability-control-of-polyaromatic-compounds">Stability Control of Polyaromatic Compounds</a></li>