Professor Andy Wilson
Andy received a BSc (Hons) 1st class at The University of Manchester Institute of Science and Technology (UMIST) in 1997 and then undertook his PhD in synthetic chemistry with Professor David A. Leigh FRS on ‘The Controlled Synthesis of Interlocked Architectures’, firstly at UMIST then at The University of Warwick, where he graduated in 2001.
He started post-doctoral research at Yale University (USA) with Professor Andrew D. Hamilton FRS on the topic of protein surface recognition, followed by further postdoctoral research with Professors E. W. (Bert) Meijer and Rint P. Sijbesma at Eindhoven University of Technology (The Netherlands) on the topic of supramolecular polymers.
In 2004 he took up his first independent academic position as a Research Lecturer at The University of Leeds, where he is now Deputy Director of the Astbury Centre for Structural Molecular Biology. Andy is also co-director of PPI-Net and served as a working group leader in the EU-COST action on Foldamers
- Deputy Director, Astbury Centre for Structural Molecular Biology
Our group is interested in using synthetic molecules to solve problems in Chemical Biology and Materials Science. The major theme of our multidisciplinary program involves the development and application of robust methods for synthesis of designed compounds. These compounds are used as tools to study molecular recognition and self-assembly using modern characterisation techniques. Current areas of interest include: the development of inhibitors of protein-protein interactions - a novel target class for pharmaceutical intervention, structural and mechanistic studies of amyloid assembly and development of supramolecular polymers based on novel hydrogen-bonding motifs.<h4>Research projects</h4> <p>Any research projects I'm currently working on will be listed below. Our list of all <a href="https://eps.leeds.ac.uk/dir/research-projects">research projects</a> allows you to view and search the full list of projects in the faculty.</p>
Research groups and institutes
- Chemical Biology and Medicinal Chemistry
<li><a href="//phd.leeds.ac.uk/project/1436-development-of-covalent-peptidomimetics-targeting-protein-protein-interactions-in-cell-division-and-cancer">Development of covalent peptidomimetics targeting protein-protein interactions in cell division and cancer</a></li>
<li><a href="//phd.leeds.ac.uk/project/1411-mapping-cellular-interactions-of-cardiovascular-ion-channels-by-chemical-proteomics">Mapping cellular interactions of cardiovascular ion channels by chemical proteomics</a></li>
<li><a href="//phd.leeds.ac.uk/project/1437-modulating-protein-protein-interactions-of-intrinsically-disordered-regions-using-a-chemical-biology-approach">Modulating Protein-Protein Interactions of Intrinsically Disordered Regions using a Chemical Biology Approach</a></li>
<li><a href="//phd.leeds.ac.uk/project/1288-understanding-and-controlling-β-strand-mediated-ppis-using-bespoke-chemical-modifications">Understanding and controlling β-strand mediated PPIs using bespoke chemical modifications</a></li>